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Example cell expressing the reporter system and aging in the YLM, as imaged using epifluorescence microscopy (see Methods for details). Video shows image sets that included fluorescence, which were taken every 2 h (the bright-field channel was imaged every 15 min). The left panel shows bright-field; the right panel shows a composite of the preCOX4-mNeonGreen signal (green) and the TIM50-mCherry signal (magenta). These data were used to generate Fig. 1 B.
