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Phagocytosis of encapsulated cryptococci treated with MAbs (50 μg/ml) that produce rim (MAbs 3C2 and 471) and puffy (MAbs 1326 and 302) capsular reactions. Serotype A cryptococci were treated with (i) IgG alone (ii) IgG and NHS, or (iii) IgG and heat-inactivated NHS (ΔNHS). Data are reported as the mean phagocytic index (number of ingested yeast cells per macrophage) from three independent experiments ± SEM.
