Table 2.
Histopathologic findings in four patients with tuberous sclerosis complex and aggressive retinal astrocytoma
| Case | Growth pattern | % necrosis | Giant cells | Plump spindle cells | Calcospherites | Bone | RD | NVI | EOE | Optic nerve invasion |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Exo | 95% | Yes | Yes | Yes | No | Yes | Yes | No | Yes |
| 2 | Exo | 70% | Yes | Yes | Yes | No | Yes | Yes | No | Yes |
| 3 | End-exo | 50% | Yes | Yes | Yes | Yes | Yes | Yes | No | Yes |
| 4 | End-exo | 60% | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
End, endophytic; EOE, extraocular extension; Exo, exophytic; NVI, iris neovascularization; RD, retinal detachment.