Table 3.
Distribution of severity of rop at randomization in eyes with high-risk prethreshold rop and percentage of conventionally managed eyes with high-risk prethreshold rop that reached threshold*
| Icrop category at randomization |
Eyes treated at high-risk prethreshold (n = 361) |
Conventionally managed eyes (n = 357) |
|||||
|---|---|---|---|---|---|---|---|
| Zone | Stage | Plus disease | No. | (%) | No. | (%) | Reaching threshold (%) |
| I | 3 | Yes | 19 | (5.3) | 19 | (5.3) | 94.7 |
| I | 3 | No | 17 | (4.7) | 16 | (4.5) | 68.8 |
| I | 1 or 2 | Yes | 14 | (3.9) | 16 | (4.5) | 87.5 |
| I | 1 or 2 | No | 99 | (27.4) | 93 | (26.1) | 49.5 |
| II | 3 | Yes | 152 | (42.1) | 156 | (43.7) | 71.8 |
| II | 3 | No | 5 | (1.4) | 4 | (1.1) | 25 |
| II | 2 | Yes | 55 | (15.2) | 53 | (14.8) | 66 |
| Total | 361 | (100) | 357 | (100) | 66.4 | ||
ICROP, International Classification of Retinopathy of Prematurity20; ROP, retinopathy of prematurity.
*
High risk was 0.15 or greater. Plus disease was defined as a degree of dilation and tortuosity of the posterior retinal blood vessels meeting or exceeding that of a standard photograph.