Figure 4.

Effect of latrunculin B (LAT-B) on miotic and accommodative responses to pilocarpine in monkeys. Pupillary and accommodative responses to topical phenylephrine (PE), 0.005% (C, D) or 0.02% (A, B) topical LAT-B, and intramuscular pilocarpine (PILO, 1.5 mg/kg) in monkeys. BL, baseline. Data are mean ± SEM for n animals (accommodation data for three animals in the 0.02% LAT-B protocol are not available). Difference between eyes was tested for differences ≠ 0.0 by the two-tailed paired t test: *P < .05; †P < .02; ‡P < .01; §P < .005; ¶P < .001.