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Unrooted tree showing the relationships between SIM-1 and other subclass B1 MBLs. The shaded triangle indicates the sequence variability observed within the IMP lineage. Accession numbers for the sequences are as follows: IMP-1, AAB30289; CcrA, P25910; BcII, P04190; VIM-1, CAB46686; BlaB, CAA65601; JOHN-1, AAK38324; EBR-1, AAN32638; IND-1, AAD20273; CGB-1, AAL55263; MUS-1, AAN63647; TUS-1, AAN63648; SPM-1, CAD37801; and GIM-1, CAF05908.
