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. 2005 Nov;49(11):4492–4499. doi: 10.1128/AAC.49.11.4492-4499.2005

TABLE 3.

Summary of virus susceptibility to pleconaril

Study No. of clinical isolates or strains Concn (μg/ml) inhibiting:
EC50 range (μg/ml)
50% of isolates or strains 80% of isolates or strains
843-043a 346 0.06 0.50 0.0008 to >3.8
843-044a 398 0.04 0.35 0.0008 to >3.8
Pooled 744 0.05 0.42 0.0008 to >3.8
Kaiser et al. (22) 46 0.04 0.54 <0.01 to >1.0
ViroPharma (24) 101b 0.08 0.30 0.008 to >4.8
a

Baseline virus isolates.

b

Prototype HRV strains.