FIG. 3.

CtERG11 gene sequence alignment of five C. tropicalis isolates (10264, 21232, 21233, and 21234 [this study] and GenBank strain 750). Only parts of DNA sequences showing differences between isolates are presented, and the number of the corresponding isolate is indicated on the left of each line. Numbers on the top of each five-line group indicate the position relative to the open reading frame. Start (+1) and stop codons are also indicated. Each mutation is positioned below the alignment by an asterisk, and corresponding nucleotides are in bold characters. The point mutation (A393T) leading to an amino acid substitution in the deduced protein sequence of the CtERG11 gene of the azole-resistant isolate 21234 is highlighted by a gray background.