TABLE 3.

MICs of polyene and azole drugs for C. tropicalis isolates^a

Antifungal	MIC (μg/ml) of indicated isolate on:
	Casitone				RPMI 1640
	21234	10264	21233	21232	21234	10264	21233	21232
Amphotericin B	0.037	0.064	0.058	0.042	0.029	0.064	0.024	0.094
Clotrimazole	>250	1	1	1	>250	4	8	1
Ketoconazole	>32	0.02	0.024	0.02	1.5	0.052	0.021	0.074
Fluconazole	>256	4	3	9	>256	0.43	0.27	0.75
Voriconazole	>32	0.6	0.025	0.046	>32	0.104	0.115	0.147

^aResults are expressed as mean values of three independent determinations. Data were obtained by the Etest procedure using antifungal strips on Casitone agar and RPMI 1640-glucose agar plates, except for clotrimazole, which was not available as an Etest strip and which was therefore tested using the microbroth dilution method. Data were analyzed with the Wilcoxon-Mann-Whitney test at unilateral risk α of 0.05. MICs were statistically different between isolate 21234 and the three other isolates (i.e., higher for azoles and lower for amphotericin B), except for amphotericin B on RMPI 1640-glucose agar.