Table 2.
Major complications in patients undergoing lumbar spine surgery
| Perioperative complications | Hypothyroidism N (%) | Whole non-hypothyroidism N (%) | P value | Matched non-hypothyroidism N (%) | P value |
|---|---|---|---|---|---|
| Medical complications | |||||
| Sepsis | 768 (0.75%) | 6,170 (0.79%) | 0.127 | 1,410 (1.39%) | < 0.001 |
| Postoperative shock | 96 (0.09%) | 665 (0.08%) | 0.409 | 260 (0.26%) | < 0.001 |
| Postoperative delirium | 1,396 (1.37%) | 6,663 (0.86%) | < 0.001 | 2,109 (2.12%) | < 0.001 |
| Acute cerebrovascular disease | 1,035 (1.02%) | 6,472 (0.84%) | < 0.001 | 1,560 (1.53%) | < 0.001 |
| Acute myocardial infarction | 2,689 (2.64%) | 18,927 (2.45%) | < 0.001 | 3,137 (3.08%) | < 0.001 |
| congestive heart failure | 2,850 (2.81%) | 13,566 (1.76%) | < 0.001 | 4,547 (4.47%) | < 0.001 |
| Deep vein thrombosis | 507 (0.49%) | 3,843 (0.50%) | 1.000 | 867 (0.85%) | < 0.001 |
| Pneumonia | 1,352 (1.33%) | 9,456 (1.23%) | 0.005 | 2,253 (2.21%) | < 0.001 |
| Pulmonary embolism | 315 (0.31%) | 2,246 (0.29%) | 0.309 | 538 (0.53%) | < 0.001 |
| Respiratory failure | 1,532 (1.51%) | 8,969 (1.16%) | < 0.001 | 2,493 (2.45%) | < 0.001 |
| Urinary tract infection | 4,313 (4.24%) | 21,452 (2.78%) | < 0.001 | 5,439 (5.34%) | < 0.001 |
| Transfusion | 8,895 (8.74%) | 45,972 (5.96%) | < 0.001 | 11,173 (10.98%) | < 0.001 |
| Wound complications | |||||
| Wound infection | 470 (0.46%) | 3,681 (0.48%) | 0.503 | 638 (0.63%) | < 0.001 |
| Wound dehiscence | 222 (0.22%) | 1,614 (0.21%) | 0.560 | 370 (0.36%) | < 0.001 |
| Other complications | |||||
| Deaths | 168 (0.17%) | 1,597 (0.21%) | 0.005 | 457 (0.45%) | < 0.001 |
| Prolonged LOS | 39,032 (38.4%) | 241,935 (31.37%) | < 0.001 | 45,458 (44.67%) | < 0.001 |