Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Box plots showing change in DIAGNOdent values from baseline to 6 months (T3-T0). Negative values indicate remineralization; positive values indicate demineralization. The dashed line at y = 0 represents no change. Boxes show IQR with median line; whiskers extend to min/max values; circles indicate outliers. Significance: ***p < 0.001, *p < 0.05. The nHAp group demonstrated the greatest reduction, significantly outperforming both CPP-ACP (p < 0.001) and fluoride varnish (p = 0.019)
