TABLE 1.
Levels of CVB/plasma-induced IFN-α in supernatants of PBMC cultures
| Subject group (n) | IFN-α production (IU/m)a induced by:
|
|
|---|---|---|
| CVB3/plasma | CVB4/plasma | |
| Healthy subjects | ||
| Adults (30) | 238 ± 123b | 100 ± 44 |
| Children (10) | 162 ± 69 | 94 ± 45 |
| IDDM patients | ||
| Adults (30) | 402 ± 178b | 260 ± 178b |
| Children (10) | 328 ± 152c | 262 ± 143c |
a
IFN-α levels were determined by dissociation-enhanced lanthanide fluoroimmunoassay and are presented as means ± standard deviations.
b
P < 0.001 versus healthy adults (Student's t test).
c
P < 0.001 versus healthy children (Student's t test).