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Neuropathogenicity of sPV1(M), PV1(M), and their mutant and revertant viruses in CD155 tg mice
| Virus | Nucleotides at positions 102 and 103 | PLD50 (log10 PFU)a |
|---|---|---|
| sPV1(M) | GG | 5.8 |
| GA sPV1(M) | GA | 2.6 |
| UA sPV1(M) | UA | 2.0 |
| GG PV1(M) | GG | 5.9 |
| GA PV1(M) | GA | 2.0 |
| PV1(M) | UA | 1.9 |
PLD50 is defined as the amount of virus that caused paralysis or death in 50% of the inoculated mice.
