FIG. 1.

Structure-based sequence alignment of all adenovirus fiber heads with known crystal structure. Structures were aligned with SARF (2), edited manually with SEAVIEW (18) and visualized with ESPript (19). Red boxes highlight conserved residues. Partially conserved residues are in red. A blue background highlights residues that contact CAR in the structure of Ad12 fiber head complexed with the D1 domain of CAR (20). The AB loop is indicated with a green box over the corresponding sequences, numbers from 1 to 19 have been assigned to residue positions within this loop and are indicated below the corresponding sequences. A yellow background box highlights the disordered region in Ad41.