FIG. 2.

IFN-γ and IL-10 production in response to LACK, ΔLACK, and peptide aa 153-176 by PBMC from LCL patients who developed lesions within 30 days of (group 1) (A) or more than 30 days after (group 2) (B) the onset of infection. Cytokine production by PBMC in culture for 7 days in the presence of LACK, ΔLACK, and peptide aa 156-173 was measured by ELISA, as described in Materials and Methods. The data are means + standard errors of the means (SEM) from results for 10 subjects in each group. ∗, P of <0.01, as determined by the Kruskal-Wallis test, for cytokine production in response to LACK versus that in response to ΔLACK or peptide aa 156-173.