FIG. 4.

Phenotype of IL-13- and IFN-γ-producing cells stimulated with SLA in LCL patients who developed lesions within 30 days of the onset of infection (group 1). IL-13 and IFN-γ production levels (A and B, respectively) were analyzed in supernatants of SLA-stimulated unfractionated cells and negatively and positively selected CD3, CD4, and CD8 cells before antigen exposure. Positively and negatively purified CD45RA, CD62L, CCR7, and CLA CD4⁺ T cells were then stimulated with SLA, and after 7 days of culture, the supernatants were harvested for determination of IL-13 and IFN-γ production levels (C and D, respectively). The data are mean levels + SEM from results for 10 LCL patients.