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. 2005 Nov;25(22):9806–9819. doi: 10.1128/MCB.25.22.9806-9819.2005

FIG. 1.

FIG. 1.

Point mutations in the cytoplasmic tail of CD40 selectively disrupt direct associations with TRAF proteins. (A) Schematic representation of WT and mutated CD40 sequences used in this study (see text for details). (B) Direct interactions of WT and mutated CD40 sequences with TRAF2, TRAF3, or TRAF6 were determined by GST pull-down assays using lysates isolated from HeLa cervical carcinoma cells, as described in Materials and Methods. NS, nonspecific.

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