TABLE 4.

Overview of the ATs of C. glutamicum

NCgl	Gene	Alias(es)	Classa		Enzymeb	Cellular functionb
			Mehta et al.	Batemann et al.
NCgl0215	aroT	pat, tyrB	I	I, II	Aromatic amino acid AT*	Aromatic amino acid synthesis (19)
NCgl0237	aspT		I		Aspartate AT*	Aspartate synthesis
NCgl0422	hemL		II	III	Glutamate semialdehyde AT	Uroporphyrinogen synthesis
NCgl0462			II	III	Butanoate metabolism	4-Aminobutyrate aminotransferase
NCgl0753	pdxR		I		Pyridoxamine-P AT	Pyridoxal-P synthesis* (19)
NCgl0780			I	I, II
NCgl0794	serC				Phosphoserine AT	Serine synthesis* (24)
NCgl1022			IV	V	Cysteine desulfurase*	Involved in NAD synthesis
NCgl1058	dapC		I	I, II	Succinyldiaminopimelate AT* (9)	Lysine synthesis* (9)
NCgl1184			IV	V	Cysteine desulfurase	Assembly of FeS complex of electron transfer flavoprotein
NCgl1343	argD		II	I	Acetylornithine AT*	Arginine synthesis* (29)
NCgl1500	sufS		IV	V	Cysteine desulfurase*	Assembly of FeS complexes
NCgl2020	hisC		I	I, II	Histidinol phosphate AT	Histidine synthesis* (19)
NCgl2123	ilvE		III	IV	Branched-chain amino acid AT*	BCAA synthesis* (26)
NCgl2227	metC	aecD	I	I, II	Cystathionine β-lyase* (15)	Methionine synthesis
NCgl2355			II	III
NCgl2491			III	IV		Glycine cleavage?
NCgl2510	avtA		I	I, II	Valine-pyruvate AT*
NCgl2515	bioA		II	III	AdoMet-aminooxononanoate AT	Biotin synthesis* (10)
NCgl2747	alaT		I	IV	Alanine AT*	Alanine synthesis*

^aThe assignments in the left column are according to Mehta et al. (20); those in the right column are according to Batemann et al. (1).

^bAn asterisk indicates experimentally derived data on enzyme activity or function, and a reference is given in parentheses for data obtained from previous studies.