FIG. 4.
Comparison of the oriT consensus nucleotide sequences (nic region) of the representative mobile plasmids and the possible nick site of the pHTβ plasmid. The oriT region containing the possible nick site of the pHT plasmid found in the inverted repeat sequences is shown. The consensus oriT region found in the pheromone-responsive conjugative plasmids (PRP) and the previously reported consensus oriT sites found in mobile plasmids are shown. The consensus oriT sequences of IncP (MOBP), the pMV158 superfamily, the MOBQ family (R1162, etc.), and the F plasmid are indicated. The consensus double-stranded replication origin (dso) of RCR plasmids is also shown. The circular marks indicate the conserved nucleotides, centrally located TG site, and an A located four residues away. The black arrowheads indicate the nick sites determined in the oriT region.