Table 1.
Neurotransmitter and metabolite levels (ng/region) in control rat brain regions.
| Brain region | Sex | 5HT | 5HIAA | DA | DOPAC | HVA |
|---|---|---|---|---|---|---|
| Cerebral cortex | Male | 267 ± 6 | 186 ± 5 | 243 ± 9 | 59 ± 2 | 42 ± 2 |
| Female | 255 ± 5 | 197 ± 5 | 230 ± 12 | 56 ± 2 | 42 ± 2 | |
| Hippocampus | Male | 113 ± 3 | 190 ± 5 | 1.3 ± 0.2 | BD | BD |
| Female | 114 ± 3 | 202 ± 5 | 1.2 ± 0.2 | BD | BD | |
| Striatum | Male | 165 ± 4 | 210 ± 5 | 541 ± 13 | 203 ± 7 | 55 ± 2 |
| Female | 173 ± 4 | 231 ± 5* | 470 ± 13* | 189 ± 6 | 50 ± 2 | |
| Midbrain | Male | 487 ± 15 | 299 ± 9 | 31 ± 1 | 16.1± 0.8 | BD |
| Female | 461 ± 13 | 324 ± 7* | 26 ± 1* | 14.1 ± 0.5 | BD | |
| Brainstem | Male | 189 ± 10 | 91 ± 6 | 4.0 ± 0.2 | 2.2 ± 0.2 | BD |
| Female | 188 ± 8 | 97 ± 7 | 3.4 ± 0.1* | 2.2 ± 0.2 | BD |
BD, below detection limit.
*Significant sex differences.