Table 1.
Chemical | References | Study type | Mutagenic mode of action |
---|---|---|---|
Amitrole | Vesselinovitch 1983 | Repeat dosing | |
Benzidine | Vesselinovitch et al. 1975b | Repeat dosing | X |
Benzo[a]pyrene | Vesselinovitch et al. 1975a | Acute exposure | X |
Dibenzanthracene | Law 1940 | Acute exposure | X |
Dichlorodiphenyltrichloroethane | Vesselinovitch et al. 1979a | Repeat dosing
Lifetime exposure |
|
Dieldrin | Vesselinovitch et al. 1979a | Repeat dosing
Lifetime exposure |
|
Diethylnitrosamine | Peto et al. 1984 | Lifetime exposure | X |
Vesselinovitch et al. 1984 | Acute exposure | ||
Dimethylbenz[a]anthracene | Meranze et al. 1969 | Acute exposure | X |
Pietra et al. 1961 | Acute exposure | ||
Walters 1966 | Acute exposure | ||
Dimethylnitrosamine | Hard 1979 | Acute exposure | X |
Diphenylhydantoin, 5,5- | Chhabra et al. 1993b | Repeat dosing
Lifetime exposure |
|
Ethylnitrosourea | Naito et al. 1981 | Acute exposure | X |
Vesselinovitch et al. 1974 | Acute exposure | ||
Vesselinovitch 1983 | Acute exposure | ||
Ethylene thiourea | Chhabra et al. 1992 | Repeat dosing
Lifetime exposure |
|
3-Methylcholanthrenea | Klein 1959 | Repeat dosing | X |
N-Methylnitrosourea | Terracini and Testa 1970 | Acute exposure | |
Terracini et al. 1976 | Acute exposure | X | |
Polybrominated biphenyls | Chhabra et al. 1993a | Repeat dosing
Lifetime exposure |
|
Safrole | Vesselinovitch et al. 1979a | Repeat dosing
Lifetime exposure |
X |
Urethane | Chieco-Bianchi et al. 1963 | Acute exposure | X |
Choudari Kommineni et al. 1970 | Acute exposure | ||
De Benedictis et al. 1962 | Acute exposure | ||
Fiore-Donati et al. 1962 | Acute exposure | ||
Klein 1966 | Acute exposure
Lifetime exposure |
||
Liebelt et al. 1964 | Acute exposure | ||
Rogers 1951 | Acute exposure | ||
Vinyl chloride | Maltoni et al. 1984 | Repeat dosing | X |
X, chemicals with a mutagenic mode of action. The chemicals listed here are from the list of more than 50 chemicals found to have carcinogenic effects from prenatal or postnatal exposures in animals [Supplementary Table S1 (http://ehp.niehs.nih.gov/docs/2005/7667/supp.pdf)].
Formerly known as 20-methylcholanthrene.