Table 1.
Major routes of elimination of drugs in the geriatric pharmacokinetic database.
| Chemical | Route of elimination | Chemical | Route of elimination |
|---|---|---|---|
| Amikacin | Renal | Lisinopril | Fecal |
| Amitriptyline | CYP2D6 | Lithium | Renal |
| Ampicillin | Renal | Meperidine | Esterase |
| Antipyrine | CYP: mixed/unknown | Mephobarbital-r | CYP2C19 |
| Atracurium | Esterase | Mephobarbital-s | CYP: mixed/unknown |
| Benazepril | Renal | Mianserin | CYP2D6 |
| Bromazepam | CYP: mixed/unknown | Midazolam | CYP3A or CYP3A4 |
| Bupivicaine | CYP1A2 | Nortriptyline | CYP2D6 |
| Chlorpheniramine | CYP2D6 | Oxazepam | Conjugation |
| Chlorzoxazone | CYP2E1 | Oxytocin | Other: sulfhydryl reduction and aminopeptidase |
| Copper | Renal | ||
| Diazepam | CYP2C19 | Paracetamol | Conjugation |
| Dicumarol | Unclassified | Pethidine | Esterase |
| Enalapril | Renal | Phenylbutazone | Conjugation |
| Enalaprilat | Renal | Phenylpropanolamine | Renal |
| Erythromycin | CYP3A or 3A4 | Piroxicam | CYP2C9 |
| Fentanyl | CYP3A or CYP3A4 | Propanolol | CYP2D6 |
| Gentamicin | Renal | Teicoplanin | Renal |
| Grepafloxacin | Unclassified | Terfenadine | Renal |
| Ibuprofen | CYP2C9 | Theophylline | CYP1A2 |
| Ketanserin | Unclassified | Valproic acid | Conjugation |
| Ketoprofen | Conjugation | Vancomycin | Renal |
| Ketorolac | Renal | Viloxazine | Unclassified |
| Lidocaine | Cyp3A or CYP3A4 |