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Overview of the database for various parameters.
| Parameter | No. of drugs | Individual data points | Data groupsa | Subjects in data groups (n) | Total no. of subjects |
|---|---|---|---|---|---|
| AUC | 17 | 163 | 21 | 317 | 480 |
| Clearance | 31 | 210 | 59 | 1,003 | 1,213 |
| Half-life | 44 | 359 | 84 | 1,312 | 1,671 |
| Vd | 26 | 153 | 51 | 996 | 1,149 |
| Total | 46 | 885 | 215 | —b | —b |
Vd, volume distribution.
Data sets where pooled (e.g., mean, SD) rather than individual data are available for the indicated parameter.
Not summed to avoid double counting.
