Table 1.
Cohort characteristics before and after propensity score matching
| Characteristic | Before matching: CUD cohort (n = 10,894) | Before matching: control cohort (n = 42,160) | P-value (Before) | Std. Diff. (Before) | After matching: CUD cohort (n = 6,858) | After matching: control cohort (n = 6,858) | P-value (After) | Std. Diff. (After) |
|---|---|---|---|---|---|---|---|---|
| Demographics | ||||||||
| Age at Index (years) | 46.4 ± 13.0 | 53.3 ± 18.1 | < 0.001 | 0.442 | 47.0 ± 13.4 | 48.1 ± 14.6 | < 0.001 | 0.081 |
| Female (%) | 34.9% | 50.9% | < 0.001 | 0.328 | 38.6% | 37.0% | 0.055 | 0.033 |
| White (%) | 52.9% | 64.8% | < 0.001 | 0.243 | 56.9% | 55.8% | 0.185 | 0.023 |
| American Indian or Alaska Native (%) | 0.6% | 0.2% | < 0.001 | 0.055 | 0.5% | 0.5% | 0.903 | 0.002 |
| Native Hawaiian or Other Pacific Islander (%) | 0.6% | 0.3% | < 0.001 | 0.042 | 0.5% | 0.6% | 0.728 | 0.006 |
| Black or African American (%) | 30.6% | 12.1% | < 0.001 | 0.463 | 24.5% | 26.8% | 0.002 | 0.053 |
| Hispanic or Latino (%) | 6.4% | 5.6% | 0.001 | 0.035 | 6.6% | 5.9% | 0.097 | 0.028 |
| Asian (%) | 1.0% | 3.5% | < 0.001 | 0.172 | 1.2% | 0.9% | 0.046 | 0.034 |
| Diagnoses | ||||||||
| Overweight and Obesity (%) | 18.3% | 6.3% | < 0.001 | 0.370 | 14.4% | 14.9% | 0.385 | 0.015 |
| Type 2 Diabetes Mellitus (%) | 30.7% | 17.8% | < 0.001 | 0.302 | 28.2% | 29.5% | 0.093 | 0.029 |
| Essential Hypertension (%) | 56.8% | 28.9% | < 0.001 | 0.590 | 48.5% | 51.5% | < 0.001 | 0.061 |
| Alcohol-Related Disorders (%) | 53.7% | 8.0% | < 0.001 | 1.137 | 36.4% | 36.0% | 0.606 | 0.009 |
| Nicotine Dependence (%) | 64.9% | 9.0% | < 0.001 | 1.420 | 45.9% | 45.7% | 0.824 | 0.004 |
| Chronic Kidney Disease (%) | 13.8% | 6.7% | < 0.001 | 0.235 | 11.9% | 12.2% | 0.564 | 0.010 |
| Hyperlipidemia, Unspecified (%) | 26.7% | 15.2% | < 0.001 | 0.286 | 23.8% | 25.1% | 0.077 | 0.030 |
| Cholelithiasis (%) | 12.1% | 7.7% | < 0.001 | 0.148 | 10.4% | 11.0% | 0.270 | 0.019 |
| Systemic Connective Tissue Disorders (%) | 2.8% | 2.1% | < 0.001 | 0.041 | 2.8% | 2.9% | 0.538 | 0.011 |