TABLE 5.
In vivo competition assays of wild-type and irgA mutants of V. cholerae
Strain | Competitive indexa
|
No. of mice | |
---|---|---|---|
Mean (SD) | Range | ||
ARM516 | 0.71 (0.46) | 0.51-1.21 | 8 |
MBG40 | 0.12 (0.11) | <0.01-0.38 | 10 |
MBG40/pCAT121 | 0.07 (0.02) | 0.04-0.09 | 4 |
The competitive index of the indicated strain was determined relative to the wild-type parent O395 in an infant mouse model. The competitive index is the output ratio adjusted for the input ratio of the two competing strains, as described in Materials and Methods.