FIG. 2.

Ability of Salmonella serotype Typhimurium strains carrying mutations in SPI1 effector genes to induce secretory and inflammatory changes in bovine ligated ileal loops at 8 h postinfection. (A) Data for fluid accumulation in loops shown as percentages of the fluid secretion elicited by the wild type (ATCC 14028 for M119 and IR715 for ZA10, ZA11, ZA13, ZA14, and STN39). The 100% line indicates the amount of fluid accumulation elicited by the Salmonella serotype Typhimurium wild type. An asterisks indicates that the fluid accumulation was significantly lower than the wild-type response (P < 0.05). (B) Inflammatory responses scored on a scale from 1 to 5 according the criteria described in Materials and Methods. WT, wild type.