Figure 2.

Main modules and functions of scMOVIR. (A) The Browse page provides an interactive portal to explore viruses and diseases, organized by the Baltimore classification and the ICD-11 system, respectively. Users can select categories to access summary cards with key information and navigate to detailed pages that present virus–disease relationships and associated datasets. (B) The Search page supports keyword queries across multiple omics datasets, including virus names, diseases, tissues, viral strains, experimental models, and specific proteins for proteomics data. Search results are displayed in both list and table formats, summarizing key information of single-cell experiments. (C) The experiment details page provides comprehensive metadata, including experimental design, sample and batch information, related experiments and datasets, analytical outcomes, interactive visualizations, downloadable files, and others. (D) The analysis and visualization module comprises a suite of interactive, high-resolution visualizations tailored to each omics layer. All plots are dynamically linked to metadata and results, enabling multi-scale interrogation of viral infection-associated cell states, molecular profiles, and intercellular communication. (E) The database incorporates two analytical tools: the Gene Signature Analysis module, which evaluates enrichment of user-defined gene sets in viral infection-related conditions, and the Integrated Viral Infection Atlas module, which enables integrative analysis of single-cell transcriptomic landscapes across various viral infections.