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Effect of fibronectin-binding proteins on S. aureus internalization into alveolar epithelial cells. SV40-AT2 cells were cocultured with either 8325-4, DU5883, or DU5883(pFnBP4) for 6 h. Extracellular S. aureus cells were killed with gentamicin. The experiment was performed three times; data from one representative experiment are shown. ∗∗, P < 0.01 versus control; ∗∗∗, P < 0.001 versus control.
