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. 2025 Dec 19;25:100332. doi: 10.1016/j.cpnec.2025.100332

Table 2.

Adjusted HRs for depression by different obesity phenotypes at baseline.

Healthy non-obese (Reference) Unhealthy non-obese BMI ≥30 only Central obesity Metabolically unhealthy obesity Sarcopenic obesity Multiple obesity phenotypes
Case 7490 5633 396 1261 4017 49 1181
Person-years 2,579,770 1,218,618 119,080.3 241,103.1 705,758.4 8009.54 113,614.9
Incidence density (1/10,000 person-years) 29.03 46.22 33.25 52.30 56.92 61.18 103.95
Model 1 1.00 1.59 (1.54,1.65) 1.14 (1.03,1.27) 1.80 (1.70,1.91) 1.97 (1.89,2.04) 2.10 (1.59,2.78) 3.59 (3.38,3.82)
Model 2 1.00 1.64 (1.58,1.70) 1.22 (1.10,1.35) 1.73 (1.63,1.84) 2.05 (1.98,2.14) 2.11 (1.59,2.79) 3.52 (3.31,3.75)
Model 3 1.00 1.43 (1.38,1.48) 1.15 (1.04,1.28) 1.60 (1.51,1.70) 1.63 (1.56,1.70) 1.86 (1.40,2.46) 2.55 (2.39,2.72)

HRs: hazard ratios.

Model 1: none of covariates.

Model 2:sex and age.

Model 3:sex, age, race, education qualifications, smoking status, drinking status, family history of depression, diabetes, and hypertension.