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Effect of CCR5 neutralization/ablation on IFN-γ–induced inflammation. (A and B) Tg– and Tg+ mice were placed on dox water and treated with anti-CCR5 or control Ig for 4 weeks. (C and D) CCR5+/+ and CCR5–/– Tg– and Tg+ mice were treated with dox water for 4 weeks. BAL cell recovery and differential were then evaluated. The values represent the mean ± SEM of evaluations in a minimum of 4 mice in each group; *P < 0.05. Eo, eosinophil; Neu, neutrophil; Lym, lymphocyte; Mac, macrophage.
