Figure 7.

Post-ischemic AP recovery and arrhythmias. (A) Representative APs during recovery upon reperfusion in control, 4′-Cl-DZP–, CsA-, and FGIN-1-27–treated hearts. (B) Recovery of APD after 5 minutes of reperfusion as a percentage of baseline APD in hearts treated with 64 μM 4′-Cl-DZP and various concentrations of CsA, indicating that the optimal concentration was 0.2 μM. (C) Plot of the recovery of APD upon reperfusion normalized to the baseline APD before ischemia in 4′-Cl-DZP– and CsA-treated hearts.