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. Author manuscript; available in PMC: 2026 Jan 17.
Published in final edited form as: Clin Cancer Res. 2025 Jul 15;31(14):3084–3095. doi: 10.1158/1078-0432.CCR-24-3168

Figure 4:

Figure 4:

Molecular landscape of low-grade serous tumors with histologic transformation. (A) Oncoprint showing summary of somatic pathogenic genetic alterations, annotated as specified in the legend. LGS-HT – low-grade serous tumors with histologic transformation. SNV – single nucleotide variant. (B) Fraction of genome altered (FGA) and tumor mutation burden (TMB) in LGS-HT, compared to reference cases of ovarian low-grade serous carcinoma (LGSC, n=100) and high-grade serous carcinoma (HGSC, n=809).