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. 2002 Jul;70(7):3557–3565. doi: 10.1128/IAI.70.7.3557-3565.2002

FIG. 1.

FIG. 1.

Time course of the serum IgG anti-rHagB response in mice immunized by the i.n. route with rHagB alone or rHagB plus MPL. Mice were immunized (∧) on days 0, 14, and 28 by the i.n. route with rHagB (20 μg) or with rHagB (20 μg) plus MPL (25 μg). Individual serum samples were collected prior to and at approximately 2-week intervals following immunization. Values are expressed as the geometric mean ×/÷ SEM. ∗, value is significantly different (P < 0.05) from those obtained in the HagB-only immunized group.