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. 2026 Jan 15;31(2):2500275. doi: 10.2807/1560-7917.ES.2026.31.2.2500275

Table 5. Immunisation effectiveness against RSV hospitalisation in children (< 2 years) residing in jurisdictions with population-based nirsevimab programmes, Queensland and Western Australia, Australia, 2024 (n = 800).

Immunisation effectiveness by age Number of RSV-positive cases Number of RSV-negative controls OR 95% CI aOR 95% CI Nirsevimab effectiveness 95% CI
Imm Unimm Imm Unimm
RSV hospitalisation
< 6 months 26 108 34 56 0.397 0.217 to 0.725 0.191a 0.071 to 0.513 80.9%a 48.7 to 92.9
< 12 months 37 222 58 99 0.284 0.177 to 0.458 0.169a 0.087 to 0.326 83.1%a 67.4 to 91.3
12–23 months 12 305 7 60 0.362 0.139 to 0.944 0.766a 0.222 to 2.645 23.4%a −100 to 77.8
RSV-associated ICU/HDU admission
< 12 months 4 15 9 6 0.177 0.039 to 0.806 0.085b 0.004 to 1.611 91.5%b −61.1 to 99.5

aOR: adjusted odds ratio; CI: confidence interval; HDU: high dependency unit; ICU: intensive care unit; Imm: immunised; OR: odds ratio; RSV: respiratory syncytial virus; Unimm: unimmunised.

a Adjusted by age group, chronic medical conditions, First Nations status, grouped by week and state.

b Adjusted by age group, chronic medical conditions, First Nations status, grouped by month and state.

First Nations status included all Aboriginal Australian and Torres Strait Islander people based on self-report on medical records.