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. 2026 Jan 5;13:1706523. doi: 10.3389/fpubh.2025.1706523

Table 2.

Mortality of type 2 diabetes in adults aged 20–54 years between 1990 and 2021 at the global and regional level.

1990 2021 1990–2021
Location Death cases Death rate Death cases Death rate Cases changeb Rate changeb EAPCa
Global 83326.35 (78973.37, 87754.46) 3.47 (3.29, 3.65) 176562.36 (163155.75, 189589.99) 4.68 (4.33, 5.03) 111.89 (92.61, 128.46) 35.11 (22.82, 45.68) 0.90 (0.84, 0.97)
High SDI 9977.47 (9739.22, 10253.59) 2.26 (2.20, 2.32) 12388.84 (11746.76, 13081.22) 2.40 (2.28, 2.53) 24.17 (16.79, 31.40) 6.24 (−0.08, 12.42) −0.08 (−0.36, 0.20)
High-middle SDI 9800.34 (9168.08, 10520.41) 1.88 (1.76, 2.02) 14561.45 (13271.27, 15994.59) 2.23 (2.03, 2.45) 48.58 (31.99, 66.82) 18.33 (5.12, 32.86) 0.32 (0.13, 0.51)
Middle SDI 29108.89 (27514.56, 30536.35) 3.71 (3.51, 3.89) 67201.80 (62569.51, 71796.85) 5.47 (5.09, 5.84) 130.86 (109.26, 150.78) 47.36 (33.57, 60.07) 1.21 (1.11, 1.31)
Low-middle SDI 21911.95 (20186.31, 23785.21) 4.67 (4.30, 5.07) 55379.51 (49803.58, 61313.33) 6.05 (5.44, 6.70) 152.74 (120.55, 184.98) 29.62 (13.11, 46.15) 0.95 (0.89, 1.00)
Low SDI 12389.75 (10976.55, 13959.86) 6.72 (5.95, 7.57) 26795.39 (23244.50, 31117.32) 5.94 (5.15, 6.90) 116.27 (84.68, 151.71) −11.59 (−24.50, 2.90) −0.57 (−0.68,-0.47)
Regions
Andean Latin America 582.23 (521.12, 657.84) 3.71 (3.32, 4.20) 1533.93 (1226.09, 1901.82) 4.71 (3.77, 5.84) 163.46 (103.10, 232.95) 26.91 (−2.16, 60.39) 0.59 (0.40, 0.78)
Australasia 136.74 (128.61, 145.00) 1.36 (1.28, 1.44) 205.99 (191.90, 221.73) 1.41 (1.32, 1.52) 50.65 (37.78, 64.96) 3.95 (−4.93, 13.82) −0.40 (−0.79,-0.02)
Caribbean 1350.21 (1240.40, 1489.56) 8.50 (7.81, 9.38) 2189.33 (1767.15, 2661.41) 9.54 (7.70, 11.60) 62.15 (30.86, 97.28) 12.28 (−9.38, 36.61) 0.38 (0.27, 0.49)
Central Asia 640.33 (597.99, 676.17) 2.15 (2.01, 2.27) 1731.27 (1488.13, 2000.54) 3.71 (3.19, 4.29) 170.37 (130.48, 212.84) 72.39 (46.95, 99.47) 1.51 (1.15, 1.87)
Central Europe 1399.69 (1350.66, 1448.58) 2.36 (2.28, 2.44) 1260.67 (1155.23, 1367.29) 2.31 (2.11, 2.50) −9.93 (−17.65,-2.47) −2.31 (−10.69, 5.78) 0.03 (−0.17, 0.23)
Central Latin America 6123.02 (5991.69, 6269.92) 8.98 (8.78, 9.19) 16251.57 (14493.67, 18169.23) 13.01 (11.60, 14.54) 165.42 (137.29, 197.89) 44.88 (29.53, 62.61) 0.92 (0.53, 1.32)
Central Sub-Saharan Africa 1854.46 (1452.25, 2304.51) 9.17 (7.18, 11.40) 4917.47 (3742.64, 6413.55) 9.05 (6.89, 11.80) 165.17 (98.40, 254.42) −1.37 (−26.20, 31.83) 0.03 (−0.08, 0.14)
East Asia 9812.12 (8492.26, 11245.90) 1.61 (1.40, 1.85) 14320.59 (11711.60, 17317.62) 1.95 (1.59, 2.35) 45.95 (14.96, 89.61) 20.68 (−4.94, 56.78) 0.45 (0.12, 0.78)
Eastern Europe 1136.04 (1044.01, 1198.45) 1.03 (0.95, 1.09) 1963.43 (1810.86, 2121.48) 1.99 (1.84, 2.15) 72.83 (57.34, 93.14) 93.54 (76.19, 116.27) 0.71 (−0.07, 1.49)
Eastern Sub-Saharan Africa 5944.66 (5127.10, 6962.66) 8.77 (7.57, 10.28) 11429.61 (9707.20, 13628.81) 6.67 (5.66, 7.95) 92.27 (57.19, 130.89) −24.02 (−37.88,-8.76) −1.18 (−1.31,-1.06)
High-income Asia Pacific 2093.27 (1970.39, 2242.51) 2.38 (2.24, 2.55) 947.52 (859.99, 1041.87) 1.13 (1.02, 1.24) −54.73 (−59.48,-49.45) −52.62 (−57.59,-47.08) −2.55 (−2.79,-2.30)
High-income North America 4136.34 (4024.51, 4268.70) 2.92 (2.84, 3.01) 5963.29 (5774.24, 6154.47) 3.55 (3.44, 3.66) 44.17 (37.82, 50.20) 21.58 (16.23, 26.67) 0.23 (−0.22, 0.68)
North Africa and Middle East 4611.69 (4094.11, 5265.39) 3.44 (3.05, 3.92) 13661.70 (11404.86, 16152.11) 4.40 (3.68, 5.21) 196.24 (133.18, 247.29) 28.09 (0.82, 50.16) 0.93 (0.78, 1.07)
Oceania 675.61 (505.57, 855.48) 25.00 (18.71, 31.66) 1755.70 (1422.52, 2181.84) 27.84 (22.55, 34.59) 159.87 (93.01, 245.14) 11.35 (−17.30, 47.89) 0.37 (0.32, 0.43)
South Asia 17665.87 (16027.07, 19059.88) 3.87 (3.51, 4.18) 45561.31 (39869.28, 51028.61) 4.98 (4.36, 5.58) 157.91 (120.12, 200.35) 28.57 (9.73, 49.73) 0.91 (0.75, 1.07)
Southeast Asia 12095.56 (10724.86, 13847.69) 5.95 (5.28, 6.81) 28284.23 (24814.82, 32016.25) 7.98 (7.00, 9.03) 133.84 (99.48, 175.81) 34.09 (14.39, 58.15) 1.03 (0.96, 1.10)
Southern Latin America 692.17 (650.18, 739.24) 3.11 (2.92, 3.32) 802.80 (748.70, 858.93) 2.40 (2.24, 2.57) 15.98 (5.33, 27.83) −22.94 (−30.02,-15.06) −1.03 (−1.20,-0.86)
Southern Sub-Saharan Africa 1533.60 (1406.74, 1675.77) 7.12 (6.53, 7.78) 4217.55 (3789.80, 4650.98) 10.73 (9.64, 11.83) 175.01 (135.58, 212.74) 50.66 (29.06, 71.33) 1.89 (1.49, 2.29)
Tropical Latin America 4370.99 (4251.02, 4487.86) 6.41 (6.24, 6.59) 6650.52 (6416.17, 6903.40) 5.70 (5.50, 5.92) 52.15 (45.35, 58.98) −11.10 (−15.08,-7.12) −0.64 (−0.77,-0.51)
Western Europe 2718.90 (2642.00, 2803.30) 1.44 (1.40, 1.48) 1936.90 (1868.61, 2010.13) 0.99 (0.95, 1.02) −28.76 (−31.77,-25.36) −31.51 (−34.40,-28.24) −1.01 (−1.20,-0.83)
Western Sub-Saharan Africa 3752.86 (3113.45, 4503.50) 5.27 (4.37, 6.32) 10976.98 (8850.20, 13130.48) 5.80 (4.68, 6.94) 192.50 (134.53, 262.69) 10.17 (−11.66, 36.61) 0.28 (0.19, 0.37)

EAPC, estimated annual percentage change; SDI, Sociodemographic Index; UI, uncertainty interval.

a

EAPC is expressed as 95% confidence interval.

b

Change shows the percentage change.