Table 2.
Adjusteda difference in FSH metabolic parameters by smoking level and 95% CIs.
| Cigarettes/dayb |
|||
|---|---|---|---|
| Parameter and cycle daysc | None (n = 186) Intercept | ≤ 9 (n = 49) β (95% CI) | ≥ 10 (n = 48) β (95% CI) |
| FSH slope | |||
| −7 to −1 | 0.02 | −0.02 (−0.04 to 0.00) | 0.02 (−0.003 to 0.04) |
| −5 to 1 | 0.04 | −0.02 (−0.05 to 0.01) | 0.02 (−0.015 to 0.06) |
| −3 to 1 | 0.09 | −0.04 (−0.10 to 0.01) | 0.02 (−0.04 to 0.07) |
| Mean daily FSH | |||
| −7 to −1 | 0.31 | −0.03 (−0.12 to 0.06) | 0.09 (−0.01 to 0.20) |
| −5 to 1 | 0.37 | −0.06 (−0.17 to 0.05) | 0.12 (0.00 to 0.24) |
| −3 to 1 | 0.40 | −0.08 (−0.21 to 0.04) | 0.14 (0.003 to 0.28) |
| −3 to 3 | 0.50 | −0.08 (−0.22 to 0.06) | 0.10 (−0.06 to 0.26) |
| 1 to 5 | 0.68 | −0.09 (−0.29 to 0.10) | 0.006 (−0.22 to 0.23) |
a
Adjusted for age, race, pregnancy history, BMI, and alcohol and caffeine consumption in mixed models for repeated measures, with weighting of FSH parameter by proportion of nonmissing within the window.
b
Smoking as reported during cycle starting with day 1; n is for the parameter with the largest numbers. These vary by a few cycles because of missing data; one outlier was excluded.
c
Days are counted with first bleed day of a cycle numbered as day 1. Data from Women’s Reproductive Health Study, California Department of Health Services.