Table 3. Multivariable analysis for survival (relapse-free and OS).

	Relapse free survival			OS
Variables	HR	95% CI	p-value	HR	95% CI	p-value
Age	1.02	1.01–1.03	0.00	1.02	1.00–1.03	0.01
Race
Caucasian	1	.	.	1	.	.
Non-Caucasian	1.11	0.85–1.46	0.45	1.15	0.87–1.51	0.33
PS
0	1	.	.	1	.	.
1	2.16	1.47–3.16	0.00	2.50	1.66–3.75	0.00
2	2.50	1.45–4.32	0.00	3.45	1.97–6.03	0.00
3	3.27	1.50–7.13	0.00	4.12	1.84–9.21	0.00
Histology
EG3	1	.	.	1	.	.
Serous	1.13	0.76–1.69	0.53	1.22	0.82–1.83	0.32
Clear cell	1.09	0.66–1.79	0.74	1.13	0.68–1.88	0.63
Carcinosarcoma	2.39	1.55–3.67	0.00	2.56	1.66–3.94	0.00
Mixed	0.94	0.61–1.43	0.76	0.89	0.57–1.37	0.59
SOE	0	.	.	0	0	1.00
Type of surgery
TAH	1	.	.	1	.	.
TAH + BSO	0.84	0.37–1.90	0.67	0.72	0.31–1.65	0.44
TAH + BSO + LN	0.70	0.30–1.61	0.40	0.57	0.25–1.31	0.18
TAH + BSO + LN +  Omentectomy	0.61	0.27–1.41	0.25	0.48	0.21–1.12	0.09
FIGO stage
I	1	.	.	1	.	.
II	2.96	1.91–5.48	0.00	2.90	1.87–4.50	0.00
III	5.98	3.93–9.10	0.00	6.16	3.98–9.53	0.00
IV	12.89	7.9420.93	0.00	10.52	6.48–17.09	0.00
p53/L1CAM
p53wt/L1CAMneg	1	.	.	1	.	.
p53wt/L1CAMpos	2.02	1.06–3.84	0.03	2.39	1.24–4.62	0.01
p53ab/L1CAMneg	2.20	1.28–3.77	0.00	2.31	1.33–4.02	0.00
p53ab/L1CAMpos	2.99	1.74–5.13	0.00	2.94	1.69–5.09	0.00
Treatment
Observation	1	.	.	1	.	.
CT with/without RT	0.37	0.25–0.57	0.00	0.35	0.23–0.53	0.00
RT and/or BT	0.54	0.36–0.83	0.00	0.65	0.43–0.99	0.05

Abbreviations: SD, standard deviation; TAH, total abdominal hysterectomy; BSO, bilateral salpingoophorectomy; LN, lymphadenectomy; ECG3, endometrioid carcinoma grade 3; CT, adjuvant chemotherapy; RT, adjuvant radiotherapy; BT, adjuvant brachytherapy