Table 2. Enrichment analysis of protein targets associated with identified genes. The table lists significantly enriched protein targets predicted to interact with the query genes. Columns indicate the protein target (Term), overlap of genes in the input set with the target’s associated genes (input genes/total target-associated genes), raw p-value, adjusted p-value (BH correction), old p-value and old adjusted p-value from previous analysis, odds ratio (measure of enrichment strength), combined score (integration of p-value and odds ratio) and the specific overlapping gene(s).
| Term | Overlap | p-value | Adjusted p-value | Old p-value | Old adjusted p-value | Odds ratio | Combined score | Genes |
|---|---|---|---|---|---|---|---|---|
| FLNA | 1/135 | 0.0134546517038701 | 0.0390965888145967 | 0 | 0 | 148.23880597014926 | 638.676575305457 | GRIK1 |
| RIF1 | 1/157 | 0.0156386355258387 | 0.0390965888145967 | 0 | 0 | 127.1923076923077 | 528.8669878232274 | HLA-DQA1 |
| DLG4 | 1/409 | 0.0404825893488036 | 0.0539530708707953 | 0 | 0 | 48.01470588235294 | 153.97755796464196 | GRIK1 |
| PRKACA | 1/440 | 0.04351685936573 | 0.0539530708707953 | 0 | 0 | 44.55353075170843 | 139.65780243417447 | GRIK1 |
| PRKCA | 1/547 | 0.0539530708707953 | 0.0539530708707953 | 0 | 0 | 35.62637362637363 | 104.01620930061436 | GRIK1 |