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(A) Effects of protein tyrosine kinase inhibition on IL-8 gene transcription. The graph shows relative IL-8 mRNA expression corrected for total mRNA by using the housekeeping gene β-actin. mRNA bands were quantified by densitometry with NIH Image 1.58. (B) Nuclear binding of the transcription factor NF-κB in TB-infected human monocytes, as detected by electromobility gel shift analysis. All data are representative of the results of three independent experiments.
