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Bacterial counts in lungs (A) and bloodstream (B) of immunocompetent and leukopenic mice infected with S. pneumoniae (means + SD [error bars] for five mice). Values that were significantly greater than those observed for infected immunocompetent mice are indicated by symbols as follows: ∗, P < 0.05; •, P < 0.01; §, P < 0.001.
