TABLE 1.

Histopathology of lung injury in pneumococcal pneumonia in leukopenic and immunocompetent mice

Condition	Histopathological scorea in mouse group at time (h)
	Leukopenic				Immunocompetent
	4	24	48	72	4	24	48	72	96
Leukocytes in lungs	0	0	0	0	1	2	3	4	4
Vascular injury	0	0	1	3	0	0	0	1	2
Surfactant in alveoli	0	0	1	0	0	1	2	3	4
Necrosis near the vessels	0	0	1	3	0	0	0	1	2
Intra-alveolar fibrosis	0	1	2	3	0	0	0	1	1
Collapsed alveoli	0	0	2	3	0	0	1	1	2

^aHistopathological score (rates signs of injuries or extent of modifications compared to uninfected controls): 0, none; 1, scarce; 2, mild; 3, moderate; 4, severe.