Table 3.
Mediation effects of depressive symptoms in LE8 components—NAFLD pathways (Adjusting for model 5’s covariates)
| LE8 components | Path coefficients and significance | Total effect β (95% CI) | Direct effect β₃ (95% CI) | Mediating effect (β₁*β₂) | Mediation proportion | Mediation significance (P value) |
|---|---|---|---|---|---|---|
| HEI-2015 diet score | β₁ = − 0.04(− 0.06, − 0.03), P < 0.001; β₂ = 0.27(0.14,0.39), P < 0.001 | − 0.03(− 0.05, − 0.02), P < 0.001 | − 0.03(− 0.04, − 0.01), P < 0.001 | − 0.0108 | 5.79% | < 0.001 |
| Physical activity score | β₁ = − 0.04(− 0.06, − 0.02), P < 0.001; β₂ = 0.28(0.15,0.41), P < 0.001 | − 0.01(− 0.02,0.00), P = 0.226 | − 0.01(− 0.02,0.01), P = 0.342 | − 0.0112 | 17.74% | < 0.001 |
| Nicotine exposure score | β₁ = − 0.12(− 0.15, − 0.09), P < 0.001; β₂ = 0.30(0.17,0.43), P < 0.001 | 0.02(0.00,0.03), P = 0.040 | 0.02(0.01,0.04), P = 0.010 | − 0.036 | − 27.55% | < 0.001 |
| Sleep health score | β₁ = − 0.14(− 0.16, − 0.11), P < 0.001; β₂ = 0.27(0.15,0.40), P < 0.001 | − 0.01(− 0.03,0.01), P = 0.188 | − 0.00(− 0.02,0.01), P = 0.558 | − 0.0378 | 46.78% | < 0.001 |
| BMI score | β₁ = − 0.04(− 0.07, − 0.02), P = 0.003; β₂ = 0.28(0.05,0.51), P = 0.019 | − 0.52(− 0.55, − 0.50), P < 0.001 | − 0.52(− 0.55, − 0.50), P < 0.001 | − 0.0112 | 0.22% | 0.024 |
| Blood lipids score | β₁ = − 0.02(− 0.04, − 0.01), P = 0.032; β₂ = 0.27(0.15,0.40), P < 0.001 | − 0.05(− 0.07, − 0.03), P < 0.001 | − 0.05(− 0.07, − 0.03), P < 0.001 | − 0.0054 | 1.53% | 0.076 |
| Blood glucose score | β₁ = − 0.02(− 0.05,0.01), P = 0.298; β₂ = 0.29(0.16,0.41), P < 0.001 | − 0.07(− 0.09, − 0.05), P < 0.001 | − 0.07(− 0.09, − 0.05), P < 0.001 | − 0.0058 | 1.21% | 0.152 |
| Blood pressure score | β₁ =− 0.01(− 0.03,0.01), P = 0.418; β₂ = 0.29(0.16,0.41), P < 0.001 | -0.05(-0.06, -0.03), P < 0.001 | − 0.05(− 0.06, − 0.03), P < 0.001 | − 0.0029 | 1.09% | 0.324 |