TABLE 1.
Age (days) of mice at immunization | Vaccine | Type of challenged | Levele of anti-PT IgG in serum (μg/ml) on day of life:
|
|
---|---|---|---|---|
18a | 25b | |||
5 | PTxc | 0.5 μg of PT | 0.3 | 3.3 |
PTx | Saline | 0.7 | 8.1 | |
AlPO4 | 0.5 μg of PT | 0.3 | 0.5 | |
7 | PTx | 0.5 μg of PT | 0.6 | 5.4 |
PTx | Saline | 0.4 | 6.4 | |
AlPO4 | 0.5 μg of PT | 0.4 | 0.7 | |
9 | PTx | 0.5 μg of PT | 0.3 | 4.7 |
PTx | Saline | 0.4 | 5.3 | |
AlPO4 | 0.5 μg of PT | 0.2 | 0.4 |
No statistical difference between any of the groups (P > 0.05).
Approximately 10-fold rise in antibody for all PTx-immunized groups (P < 0.05).
TNM-inactivated PTx vaccine.
On day 18 of life.
Geometric mean.