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. 2002 Aug;70(8):4600–4608. doi: 10.1128/IAI.70.8.4600-4608.2002

TABLE 1.

Effect of age on anti-PT IgG antibody response following primary immunization

Age (days) of mice at immunization Vaccine Type of challenged Levele of anti-PT IgG in serum (μg/ml) on day of life:
18a 25b
5 PTxc 0.5 μg of PT 0.3 3.3
PTx Saline 0.7 8.1
AlPO4 0.5 μg of PT 0.3 0.5
7 PTx 0.5 μg of PT 0.6 5.4
PTx Saline 0.4 6.4
AlPO4 0.5 μg of PT 0.4 0.7
9 PTx 0.5 μg of PT 0.3 4.7
PTx Saline 0.4 5.3
AlPO4 0.5 μg of PT 0.2 0.4
a

No statistical difference between any of the groups (P > 0.05).

b

Approximately 10-fold rise in antibody for all PTx-immunized groups (P < 0.05).

c

TNM-inactivated PTx vaccine.

d

On day 18 of life.

e

Geometric mean.