TABLE 2.
Characteristics of mice on the day of aerosol challenge
| Characteristicb | Value for group challenged with:
|
|||
|---|---|---|---|---|
| PTx
|
AlPO4 (n = 9) | |||
| 2.5 μg (n = 13) | 0.5 μg (n = 12) | 0.1 μg (n = 12) | ||
| Sex Ratio (female/male) | 8/5 | 5/7 | 8/4 | 7/2 |
| Mean wt ± SD (g) | ||||
| Females | 16.1 ± 0.3 | 16.8 ± 0.4 | 16.9 ± 0.2 | 15.4 ± 0.2 |
| Males | 19.4 ± 0.2 | 19.0 ± 0.3 | 18.8 ± 0.6 | 17.9 ± 0.4 |
| Mean WBC count ± SD (103 cells/mm3) | 5.9 ± 0.7 | 5.5 ± 0.5 | 5.2 ± 0.5 | 5.9 ± 0.4 |
| Anti-PT IgG titer (μg/ml) | 26.5 | 3.3 | 0.8 | 0.5 |
a
Female recipients of the PTx dose of 0.1 μg were slightly larger than female recipients of the PTx dose of 2.5 μg (P = 0.04); otherwise, there were no differences between any of the groups (P > 0.05).
b
Weights and WBC counts are presented as means ± standard deviations and antibody titers are presented as geometric means.