Table 2.

The comparison of diagnostic performance of different detection methods.

Detection method	TP	FP	TN	FN	Agreement	Positive agreement	Negative agreement	PPV	NPV	TAT (Day)
mNGS	72	15	108	51	0.732	0.585	0.878	0.828	0.679	1.83 (1.05, 2.10)
Culture	16	6	117	107	0.541	0.130	0.951	0.727	0.522	6.86 (5.05, 7.00)
Conventional methods	48	22	103	73	0.614	0.397	0.824	0.686	0.585	4.08 (1.26, 5.28)
Combined methods	88	27	95	36	0.744	0.710	0.779	0.765	0.725	-

TP, true positive; FP, false positive; TN, true negative; FN, false negative; PPV, positive predictive value; NPV, negative predictive value. TAT, turnaround time, defined as the entire duration from sample submission to the issuance of the official microbial detection report.