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. 2025 Dec 23;16:2470. doi: 10.1038/s41598-025-32252-y

Table 1.

Baseline characteristics of patients according to LBMI.

Q1, n = 2,685 Q2, n = 2,683 Q3, n = 2,684 Q4, n = 2,683 P trend
LBMI categories, range 8.5–15.8 12.4–16.9 13.3–17.9 14.2–29.2
LBMI (male) 8.5–15.8 15.8–16.9 16.9–17.9 17.9–29.2
LBMI (female) 9.7–12.4 12.4–13.3 13.3–14.2 14.2–26.6
Men, n (%) 1,723 (64.2) 1,722 (64.2) 1,722 (64.2) 1,722 (64.2)
Age, years, mean ± SD 75.5 ± 11.1 71.8 ± 11.2 69.4 ± 11.0 65.0 ± 12.6 < 0.001
FMI, mean ± SD 5.0 ± 1.7 6.3 ± 1.8 7.4 ± 2.0 9.3 ± 3.0 < 0.001
FMI (male) 4.3 ± 1.6 5.4 ± 1.3 6.2 ± 1.3 7.7 ± 2.0 < 0.001
FMI (female) 6.2 ± 1.1 8.0 ± 0.9 9.5 ± 0.9 12.2 ± 2.2 < 0.001
BMI, kg/m2, mean ± SD 19.3 ± 1.9 22.0 ± 1.4 24.0 ± 1.3 27.7 ± 3.0 < 0.001
Risk factors, n (%)
 Hypertension 2,030 (75.6) 2,067 (77.0) 2,232 (83.2) 2,314 (86.3) < 0.001
 Dyslipidemia 1,192 (44.4) 1,460 (54.4) 1,666 (62.1) 1,813 (67.6) < 0.001
 Diabetes mellitus 720 (26.8) 770 (28.7) 843 (31.4) 1,016 (37.9) < 0.001
 Smoking 1,565 (58.3) 1,536 (57.3) 1,508 (56.2) 1,577 (58.8) 0.92
 Drinking 1,006 (37.5) 1,073 (40.0) 1,091 (40.7) 1,039 (38.7) 0.29
 Atrial fibrillation 799 (29.8) 621 (23.2) 541 (20.2) 459 (17.1) < 0.001
 Chronic kidney disease 1,042 (38.8) 917 (34.2) 824 (30.7) 780 (29.1) < 0.001
 History of stroke, n (%) 437 (16.3) 412 (15.4) 405 (15.1) 388 (14.5) 0.07
Stroke subtype, n (%)
 Cardioembolism 743 (27.7) 573 (21.4) 503 (18.7) 406 (15.1) < 0.001
 Small-vessel occlusion 742 (20.4) 868 (32.4) 912 (34.0) 958 (35.7) < 0.001
 Large-artery atherosclerosis 439 (16.4) 465 (17.3) 478 (17.8) 485 (18.1) 0.08
 Unclassified 761 (28.3) 777 (29.0) 791 (29.5) 834 (31.1) 0.03
Neurological severity
 NIHSS score, median (IQR) 3 (1–7) 3 (1–5) 2 (1–5) 2 (1–4) < 0.001
 Reperfusion therapy, n (%) 322 (12.0) 334 (12.5) 317 (11.8) 267 (10.0) 0.01

Data are expressed as mean ± SD, median (interquartile range), or n (%). Q1–Q4 indicate the quartiles of lean body mass index.

BMI, body mass index; FMI, fat mass index; IQR, interquartile range; LBMI, lean body mass index; Ptrend, P value for trend; SD, standard deviation; NIHSS, National Institutes of Health Stroke Scale.