Table 2.

Association between LBMI and functional outcomes at 3 months.

	Events, n (%)	Age and sex-adjusted			MV-adjusted			MV and FMI-adjusted*
		OR	(95% CI)	P	OR	(95% CI)	P	OR	(95% CI)	P
Poor functional outcome
Q1 (8.5–15.8), n = 2685	959 (35.7)	1.00	(reference)		1.00	(reference)		1.00	(reference)
Q2 (12.4–16.9), n = 2683	611 (22.8)	0.63	(0.56–0.72)	< 0.001	0.65	(0.56–0.75)	< 0.001	0.66	(0.57–0.78)	< 0.001
Q3 (13.3–17.9), n = 2684	519 (19.3)	0.59	(0.52–0.67)	< 0.001	0.63	(0.54–0.73)	< 0.001	0.65	(0.55–0.78)	< 0.001
Q4 (14.2–29.2), n = 2683	469 (17.5)	0.65	(0.56–0.74)	< 0.001	0.67	(0.57–0.79)	< 0.001	0.72	(0.57–0.90)	0.004
Functional dependency
Q1 (8.5–15.8), n = 2559	833 (32.6)	1.00	(reference)		1.00	(reference)		1.00	(reference)
Q2 (12.4–16.9), n = 2636	564 (21.4)	0.67	(0.59–0.76)	< 0.001	0.68	(0.58–0.79)	< 0.001	0.69	(0.59–0.81)	< 0.001
Q3 (13.3–17.9), n = 2650	485 (18.3)	0.63	(0.55–0.72)	< 0.001	0.67	(0.57–0.78)	< 0.001	0.68	(0.57–0.82)	< 0.001
Q4 (14.2–29.2), n = 2653	439 (16.6)	0.70	(0.60–0.80)	< 0.001	0.70	(0.60–0.83)	< 0.001	0.73	(0.58–0.93)	0.009

Poor functional outcome and functional dependency were defined as modified Rankin Scale scores of 3–6 and of 3–5 at 3 months after stroke onset, respectively. Lean body mass index was categorized into four groups according to quartiles by sex, respectively.

Multivariable model included age, sex, hypertension, dyslipidemia, diabetes mellitus, smoking, drinking, atrial fibrillation, chronic kidney disease, history of stroke, stroke subtype (cardioembolism, small-vessel occlusion, large-artery atherosclerosis, or others), National Institutes of Health Stroke Scale score on admission, and reperfusion therapy.

LBMI, lean body mass index; MV, multivariable; FMI, fat mass index; OR, odds ratio; CI, confidence interval.

*Fat mass index was added to multivariable model.