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. 2026 Jan 16;16:2398. doi: 10.1038/s41598-025-89666-x

Table 4.

Performance comparison between healthy and each diseased class by adopting a sigmoid activation function at the classification layer. (CA: classwise accuracy (%), BACC: Balanced Accuracy (%)).

Input Class Precision Recall F1 Score CA Specificity Sensitivity BACC
Simple Images H vs G H 0.92 0.83 0.87 82.63 0.82 0.87 84.99
G 0.74 0.87 0.80 87.35
H vs DR H 0.96 0.94 0.95 93.56 0.93 0.94 93.85
DR 0.90 0.94 0.92 94.14
Concatenated Images H vs G H 0.95 0.68 0.79 67.52 0.97 0.93 80.31
G 0.62 0.93 0.74 93.10
H vs DR H 0.94 0.83 0.88 82.95 0.82 0.91 87.21
DR 0.76 0.91 0.83 91.48
With OD H vs G H 0.93 0.82 0.87 81.67 0.81 0.89 85.66
G 0.73 0.90 0.81 89.65
H vs DR H 0.96 0.91 0.94 90.99 0.90 0.94 92.56
DR 0.86 0.94 0.90 94.14
With vessels H vs G H 0.87 0.80 0.83 80.06 0.80 0.78 77.89
G 0.69 0.79 0.73 75.73
H vs DR H 0.93 0.93 0.93 92.60 0.92 0.88 90.71
DR 0.88 0.89 0.88 88.82
Without feature selection H vs G H 0.89 0.81 0.85 81.35 0.81 0.82 82.05
G 0.71 0.83 0.77 82.75
H vs DR H 0.94 0.92 0.93 91.63 0.91 0.89 90.76
DR 0.87 0.90 0.88 89.89
Proposed* (Inline graphic: 1.0, Inline graphic: 1.0, Inline graphic: 1.0) H vs G H 0.95 0.71 0.81 71.38 0.71 0.93 82.24
G 0.65 0.93 0.76 93.10
H vs DR H 0.97 0.88 0.92 88.42 0.88 0.95 92.02
DR 0.83 0.95 0.89 95.21