Table 4.

Associations between Alzheimer’s disease (AD) genetic risk factors and AD or late-onset epilepsy (LOE), multi-task elastic net modeling sample (subset of UCLA ATLAS patient) (N = 9,986)^a.

Outcome	N	APOE-ε4 count		AD PRS without APOE region
		OR [95% CI]	P-value	OR [95% CI]	P-value
AD	9,986	2.85 (2.34, 3.48)	< 0.001*	1.15 (1.04, 1.27)	0.01*
LOE	9,986	1.20 (0.99, 1.45)	0.053	1.03 (0.95, 1.12)	0.52

AD Alzheimer’s disease, CI confidence interval.

[a]Basic Model adjustments include age at last visit, sex, and ancestry-specific principal components.