Table 2.

Comparison of state-of-art graph problem-based molecular docking solvers

Solvers	Implementation modality	Specific problem	Problem scale	Success probability reported	Postprocessing algorithms necessary?	Experimental equipment fo otprint	Scalability
RRAM-based p-computer (this work)	Experimental (Integrated Electronics)	MWCP	42 nodes	72%	No	6.5 × 4 mm2a	Good
GBS + Postprocessing49	Simulated	MWCP	24 nodes	~70%	Yes	–	Poor
GBS (“Abacus”) + Postprocessing50	Experimental (Free-Space Optics)	MWCP	28 nodes	∽32%	Yes	2m2b	Poor
DC-QAOA52	Simulated	MWCP	12 nodes	∽51%	No	–	Poor
Photonic Processor51	Experimental (Integrated Photonics)	MCP	9 nodes	–	No	50 mm2b	Poor

^aOnly chip size is considered. This p-computer is implemented on a printed circuit board (PCB) that integrates a RRAM-CMOS chip.

^bEstimated value.